End Stage Renal disease (ESRD) a affects 1.5 to 2 million people worldwide. when dialysis is available, it can be life sustaining. But the short term solution is time consuming and expensive and does not replace all of the functions of a healthy kidney.
Meanwhile the global shortage of donors, means the hundreds and thousands of people die each year waiting for kidney transplant. Scientist at UCSF are leading a research project with partners nationwide to help these patients.
The working to develop a small implantable device that replicates many natural functions of the kidneys.
Super efficient membrane created using silicon nano technology will filter toxins from the blood without requiring pumps or electrical powers. while a bio-reactor containing specially engineered kidney to tubal cells will perform other renal activities maintaining appropriate water volume in the blood, electrolyte balance and metabolic functions.
These two advance technologies will makeup small bio-compatible device, that attaches to the circulatory system and removes toxins to the bladder as waste. The artificial kidney will allow the patient to live untethered from dialysis machines eat and drink more normally and live there lives more freely. completion of this ambitious project will profoundly improve the quality and length of life for patients with kidney failure.
As well as reduce the cost as personal toll of this devastating disease.